This time I will summarize the literature on the disease
lupus or systemic lupus erythematosus, ranging from understanding the causes of
disease and lupus, characteristics or symptoms and treatment of lupus. No need
to dwell width, let's start now.
Lupus Disease:
Lupus disease is a form of autoimmune disease, meaning
the body kekabalan system (immune) instead attack the cells, tissues and organs
of the body's own healthy Persistent causing chronic inflammation. In other
words Lupus is defined as a chronic inflammatory autoimmune disease.
Inflammation caused by lupus can affect many body systems
including: joints, skin, kidneys, blood cells, brain, heart and lungs, causing
a lot of symptoms or clinical manifestations are diverse.
Therefore Lupus is difficult to detect because the signs
and symptoms are often similar to other diseases. However, signs and symptoms
of lupus disease is the most distinctive facial rash that resembles the wings
of a butterfly (rash on both cheeks) also known as malar rash.
Some people are born with a tendency to develop the
disease lupus, which may be triggered by infections, certain drugs or even
sunlight. Although there is no definitive drugs to cure the disease lupus, but
treatment can help control effort lupus symptoms that arise.
Causes of Lupus Disease:
Lupus disease is caused by the immune system that attacks
healthy tissues in the body. It can occur as a result of the possibility of a
combination of genetics and environment. Since it has been known that people
with lupus tendencies (inherited) disease lupus may develop when they are in
contact with something in the environment that can trigger lupus symptoms.
However, the exact cause of lupus is unknown. However it has been known for
some potential triggers, including:
Sunlight.
Exposure to sunlight can cause lupus because the people
who are vulnerable can cause lesions on the skin which is a symptom of lupus
disease or internal trigger a response.
Drugs.
Lupus can be triggered by some kind of anti-seizure
medications, blood pressure medications and antibiotics. People who her lupus
symptoms arise when taking medication is usually the lupus disease symptoms
will disappear when they stop taking the drug.
Lupus is not contagious, so do not ask spread of the
disease lupus. However, the risk can be lowered.
Symptoms of Lupus Disease:
As mentioned above, lupus can affect various organ
systems, so that the symptoms are very varied. However, there are symptoms or
traits common lupus disease, that we can grasp as a reference that a person
suspected of having lupus.
Here, there are 11 characteristics of lupus disease (11
Criteria for Lupus / SLE). If a person has at least four of the following
symptoms, then it positive lupus (systemic lupus erythematosus):
1. Butterfly Rash - Rash with images like butterfly
wings, that on both cheeks to the nose as the center (body)
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| cause of lupusmalar rash characteristic of lupus |
2. Discoid Rash - A rash is quite "classic"
looks red disc-shaped section clearer edges, and usually occurs on the face,
scalp, and neck. This rash often leave scars. Discoid Rash can stand alone on
discoid lupus. Read: Types of Lupus Disease
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Discoid rash as a symptom of lupus
discoid rash in lupus
|
4. Oral ulcers - sores continuous or intermittent, either
on the tongue or in any part of the oral cavity.
5. Arthritis (Arthritis) - national Trade in the joints
that cause pain, redness, swelling even.
6. Serositis - This is an inflammation of the lining of
the lungs recognized as Pleurisy (Inflammation of the lining of the lung), and
also the lining of the heart, known as pericarditis (inflammation of the lining
of the heart), causing sharp chest pain symptoms, especially when coughing and
pull breath in, sometimes can also cause shortness of breath.
7. Disorders of the kidney - Kidney Disorders in lupus
disease characterized by the discovery of protein in the urine (proteinuria) or
precipitate (sediments) are also found in the urine (this can be seen under a
microscope).
8. Neurological Disorders and Psychosis - lupus can
affect the brain and nervous system which can cause headaches, confusion,
visual disturbances such as hallucinations, and even seizures. - Applies in the
absence of drugs known to cause this state-
9. Abnormalities in Blood - Hemolytic anemia (anemia due
to rupture of red blood cells), Low White Blood Cell counts (low white blood
cells) or Low platelet counts (platelets or low platelets).
10. Immunologic Disorders - disorders characterized by
cell immunity LE Positive, Anti-DNA: antibody titers native DNA in normal,
Anti-Sm: presence of antibody to Sm nuclear antigen, a false positive
serological test for syphilis known to be positive for at least 6 months and
confirmed by Treponema pallidum immobilization or fluorescent treponemal
antibody absorption test
11. Positive ANA (Antinuclear Antibody) - Abnormal
antinuclear antibody titers by immunofluorescence or equivalent test at any
point in time.
Treatment of Lupus Disease:
Lupus Treatment depends on the signs and symptoms alone,
since not all of the symptoms usually show up on someone. Because lupus is a
chronic disease that requires long-term treatment, the symptoms and signs
munculpun should not all be treated should be carefully considered because of
the benefits and risks of treatment (medication side effects).
Lupus drug most commonly used to control lupus include:
Drugs non-steroidal anti-inflammatory (NSAID=
non-steroidal anti-inflammatory drugs).
NSAIDs Over-the-counter or sold freely, such as naproxen
and ibuprofen, can be used to treat pain, swelling and fever associated with
lupus. NSAIDs should be stronger with a doctor's prescription. Side effects of
NSAIDs include: stomach bleeding, kidney problems and an increased risk of
heart problems.
Antimalarial Drugs.
Drugs commonly used to treat malaria are also used as a
cure lupus, such as hydroxychloroquine (Plaquenil), can also help control
lupus. Side effects can include abdominal pain and, very rarely, damage to the
retina of the eye.
Corticosteroids Drugs
Prednisone and other corticosteroids are used as a type
of lupus drug since it can fight inflammation, but often produce long-term side
effects - including weight gain, easy bruising, bone loss (osteoporosis), high
blood pressure, diabetes and increased risk of infection. The risk of side
effects increases with the magnitude of the dose and long-term therapy.
Immune suppressant Drugs.
Drugs that suppress the immune system may help in cases
of severe lupus. For example cyclophosphamide, azathioprine, mycophenolate,
leflunomide and methotrexate. Potential side effects of the drug lupus include:
an increased risk of infection, liver damage, decreased fertility and increased
risk of cancer. A new drug, belimumab (Benlysta) also reduce lupus symptoms in
some people. Side effects such as nausea, diarrhea and fever
If you experience symptoms or lupus
characteristics as above, immediately consult a doctor to get proper diagnosis
and treatment.
Information By:keepourlive.blogspot.com
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